Chronic HBV infection impairs the glucose metabolism and effector function of NK cells via HBsAg/IL-15/mTOR axis

Abstract Natural killer (NK) cell function is impaired in patients with chronic hepatitis B (CHB) infection; however, the underlying mechanisms are not fully understood. Here, we collected the blood samples from healthy donors (HDs) and patients with CHB, and then analyzed the characteristics of NK...

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Bibliographic Details

Published in:	Cell Death and Disease
Main Authors:	Yating Yu, Zixuan Wang, Ailu Yang, Yucan Wang, Cuiping Bao, Li Zhuo, Qiuju Han, Huajun Zhao, Jian Zhang
Format:	Article
Language:	English
Published:	Nature Publishing Group 2025-10-01
Online Access:	https://doi.org/10.1038/s41419-025-08069-y