DNA damage measurements within tissue samples with Repair Assisted Damage Detection (RADD)

Exposures to genotoxic carcinogens and reactive species result in strand breaks and a spectrum of covalent modifications to DNA that can induce mutations and contribute to the initiation and progression of cancer. Measurements of DNA damage within tissue or tumor samples can serve as a biomarker for...

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Bibliographic Details

Published in:	Current Research in Biotechnology
Main Authors:	Kevin J. Lee, Elise Mann, Luciana Madeira da Silva, Jennifer Scalici, Natalie R. Gassman
Format:	Article
Language:	English
Published:	Elsevier 2019-11-01
Subjects:	DNA damage DNA adducts Tissue Ovarian cancer DNA strand breaks Glycosylases
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590262819300103