The role of cognitive reserve in white matter hyperintensities: from cognitive aging to Alzheimer's spectrum

Abstract INTRODUCTION White matter hyperintensities (WMHs) are characteristic of Alzheimer's disease (AD), and cognitive reserve (CR) protects cognitive function. However, whether WMHs mediate the CR–cognition relationship remains unclear. METHODS Brain imaging, clinical features, and neuropsyc...

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Bibliographic Details

Published in:	Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring
Main Authors:	Yu‐Ruei Lin, Wei‐Lu Lee, Jong‐Ling Fuh
Format:	Article
Language:	English
Published:	Wiley 2025-07-01
Subjects:	Alzheimer's disease cognitive function cognitive reserve mediation effect white matter hyperintensity
Online Access:	https://doi.org/10.1002/dad2.70167