PRRSV Vaccine Strain-Induced Secretion of Extracellular ISG15 Stimulates Porcine Alveolar Macrophage Antiviral Response against PRRSV

Porcine reproductive and respiratory syndrome virus (PRRSV) has disrupted the global swine industry since the 1980s. PRRSV-host interactions are largely still unknown but may involve host ISG15 protein. In this study, we developed a monoclonal antibody (Mab-3D5E6) specific for swine ISG15 (sISG15) b...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Hongbin Liu, Bingjun Shi, Zhigang Zhang, Bao Zhao, Guangming Zhao, Yijing Li, Yuchen Nan
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Subjects:	interferons PRRSV ISG15 macrophage interferons-stimulated genes cytokine
Online Access:	https://www.mdpi.com/1999-4915/12/9/1009