Dexmedetomidine and levobupivacaine co-loaded, transcriptional transactivator peptide modified nanostructured lipid carriers or lipid–polymer hybrid nanoparticles, which performed better for local anesthetic therapy?

Local anesthetics (LAs) have been widely applied in clinic for regional anesthesia, postoperative analgesia, and management of acute and chronic pain. Nanostructured lipid carriers (NLCs) and lipid–polymer hybrid nanoparticles (LPNs) are reported as good choices for LA therapy. Transactivated transc...

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Bibliographic Details

Published in:	Drug Delivery
Main Authors:	Min Li, Shuo Feng, Huaixin Xing, Yingui Sun
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-01-01
Subjects:	transdermal delivery local anesthetic levobupivacaine dexmedetomidine cell penetrating peptides
Online Access:	http://dx.doi.org/10.1080/10717544.2020.1831105