The RNA Demethylases ALKBH5 and FTO Regulate the Translation of ATF4 mRNA in Sorafenib-Treated Hepatocarcinoma Cells

Translation is one of the main gene expression steps targeted by cellular stress, commonly referred to as translational stress, which includes treatment with anticancer drugs. While translational stress blocks the translation initiation of bulk mRNAs, it nonetheless activates the translation of spec...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Pauline Adjibade, Sergio Di-Marco, Imed-Eddine Gallouzi, Rachid Mazroui
Format:	Article
Language:	English
Published:	MDPI AG 2024-08-01
Subjects:	stress response translation regulation ALKBH5 FTO RNA methylation
Online Access:	https://www.mdpi.com/2218-273X/14/8/932