GelMA hydrogel dual photo-crosslinking to dynamically modulate ECM stiffness

The dynamic nature of the extracellular matrix (ECM), particularly its stiffness, plays a pivotal role in cellular behavior, especially after myocardial infarction (MI), where cardiac fibroblasts (cFbs) are key in ECM remodeling. This study explores the effects of dynamic stiffness changes on cFb ac...

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Bibliographic Details

Published in:	Frontiers in Bioengineering and Biotechnology
Main Authors:	Josephina J. H. M. Smits, Atze van der Pol, Marie José Goumans, Carlijn V. C. Bouten, Ignasi Jorba
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-06-01
Subjects:	GelMA mechanical memory cardiac fibroblast (cFb) ECM stiffness tissue engineeering
Online Access:	https://www.frontiersin.org/articles/10.3389/fbioe.2024.1363525/full