Effect and Mechanism of TFAM on Chemotherapy Resistance in Ovarian Cancer Cells Through Metabolic Reprogramming Regulation

ObjectiveTo investigate the role of mitochondrial transcription factor A (TFAM) in platinum-resistant ovarian cancer cells and its effects on metabolic reprogramming and sensitivity to platinum-based drugs MethodsThe mitochondrial function and metabolic characteristics of platinum-resistant ovarian...

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Bibliographic Details
Published in:Zhongliu Fangzhi Yanjiu
Main Authors: Lingling FAN, Reziwanguli·WUBULI, Linglan LU, Lili HAN
Format: Article
Language:Chinese
Published: Magazine House of Cancer Research on Prevention and Treatment 2025-05-01
Subjects:
mitochondrial transcription factor a
aerobic glycolysis
oxidative phosphorylation
ovarian cancer
chemotherapy resistance
Online Access:http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1072

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http://www.zlfzyj.com/cn/article/doi/10.3971/j.issn.1000-8578.2025.24.1072

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