Effects of Expression of Streptococcus pneumoniae PspC on the Ability of Streptococcus mitis to Evade Complement-Mediated Immunity

Streptococcus pneumoniae and Streptococcus mitis are genetically closely related and both frequently colonise the naso-oropharynx, yet S. pneumoniae is a common cause of invasive infections whereas S. mitis is only weakly pathogenic. We hypothesise that sensitivity to innate immunity may underlie th...

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Bibliographic Details

Published in:	Frontiers in Microbiology
Main Authors:	Helina Marshall, Ricardo J. José, Mogens Kilian, Fernanda C. Petersen, Jeremy S. Brown
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-11-01
Subjects:	Streptococcus pneumoniae Streptococcus mitis PspC complement Factor H
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2021.773877/full