A systems biology approach to prediction of oncogenes and molecular perturbation targets in B‐cell lymphomas

Abstract The computational identification of oncogenic lesions is still a key open problem in cancer biology. Although several methods have been proposed, they fail to model how such events are mediated by the network of molecular interactions in the cell. In this paper, we introduce a systems biolo...

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Bibliographic Details

Published in:	Molecular Systems Biology
Main Authors:	Kartik M Mani, Celine Lefebvre, Kai Wang, Wei Keat Lim, Katia Basso, Riccardo Dalla‐Favera, Andrea Califano
Format:	Article
Language:	English
Published:	Springer Nature 2008-02-01
Subjects:	B‐cell lymphoma drug mechanism‐of‐action (MOA) gene network interactome oncogene
Online Access:	https://doi.org/10.1038/msb.2008.2