The collective lie in ketamine therapy: a call to realign clinical practice with neurobiology

In recent years, ketamine therapy has become increasingly entangled with psychedelic culture, leading to widespread misinterpretation of its therapeutic mechanism. This manuscript challenges the prevailing narrative that positions ketamine as a consciousness-expanding agent or psychotherapy enhancer...

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Bibliographic Details

Published in:	Frontiers in Psychiatry
Main Authors:	Charles Miller, Bryan Lopes, Anna McCurdy
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-09-01
Subjects:	ketamine neuroplasticity psychoplastogen treatment-resistant depression (TRD) ketamine-assisted psychotherapy (KAP) NMDA receptor antagonist
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1610335/full