Intravenously administered iron oxide nanoparticles with different coatings reversibly perturb immune cells in peripheral blood without inducing toxicity in mice

IntroductionIron oxide nanoparticle formulations are widely used in clinical applications and have recently been explored for hyperthermia therapy, cancer imaging and treatment. Here, we report the effects of intravenously injected pegylated or poly acrylic acid decorated iron oxide nanoparticles co...

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Bibliographic Details

Published in:	Frontiers in Toxicology
Main Authors:	Preethi Korangath, Chun-Ting Yang, Sean Healy, Cordula Grüttner, Kathleen Gabrielson, Robert Ivkov
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	iron oxide nanoparticles immunotoxicity biodistribution PEGylated bionized nanoferrite nanoparticles Micromer® toxicity
Online Access:	https://www.frontiersin.org/articles/10.3389/ftox.2025.1673416/full