The CHO Cell Clustering Response to Pertussis Toxin: History of Its Discovery and Recent Developments in Its Use

Chinese hamster ovary (CHO) cells respond to pertussis toxin (PT) with a novel clustering pattern, which is dependent on biologically active PT. Since its description in 1983, this cellular response has been refined and used extensively for detection and quantification of PT activity, as well as ant...

Full description

Bibliographic Details
Published in:Toxins
Main Authors: Mary C. Gray, Richard L. Guerrant, Erik L. Hewlett
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Subjects:
Online Access:https://www.mdpi.com/2072-6651/13/11/815