Engineered spermidine-secreting Saccharomyces boulardii ameliorates colitis and colon cancer in mice

Abstract Experimental studies suggest that the probiotic yeast Saccharomyces boulardii can mitigate the symptoms of inflammatory bowel disease. However, these results are equivocal and S. boulardii probiotic therapy has not gained widespread acceptance in clinical practice. To assess whether the the...

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التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Scientific Reports
المؤلفون الرئيسيون:	Mahdi Mohaqiq, Roger Palou, Ruizhen Li, Guijun Zhang, Het Vaishnav, Florance Parweez, Terence Moyana, Damian Carragher, D. W. Cameron, Timothy Ramsay, Almer M. van der Sloot, Sanjay Murthy, Brian K. Coombes, Mike Tyers, X. Johné Liu
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Nature Portfolio 2025-08-01
الموضوعات:	Spermidine S. boulardii Inflammatory bowel disease Colitis Colon cancer
الوصول للمادة أونلاين:	https://doi.org/10.1038/s41598-025-16736-5