A Comprehensive Atlas of E3 Ubiquitin Ligase Mutations in Neurological Disorders
Protein ubiquitination is a posttranslational modification that plays an integral part in mediating diverse cellular functions. The process of protein ubiquitination requires an enzymatic cascade that consists of a ubiquitin activating enzyme (E1), ubiquitin conjugating enzyme (E2) and an E3 ubiquit...
| Published in: | Frontiers in Genetics |
|---|---|
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2018-02-01
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| Subjects: | |
| Online Access: | http://journal.frontiersin.org/article/10.3389/fgene.2018.00029/full |