Emerging Roles of Osteoclasts in the Modulation of Bone Microenvironment and Immune Suppression in Multiple Myeloma

Multiple myeloma (MM) is one of the most common forms of hematologic malignancy resulting from cancerous proliferation of mature malignant plasma cells (MPCs). But despite the real improvement in therapeutics in the past years, it remains largely incurable. MM is the most frequent cancer to involve...

Full description

Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Anna Mansour, Abdelilah Wakkach, Claudine Blin-Wakkach
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-08-01
Subjects:	osteoimmunology osteoclast multiple myeloma myeloma bone disease immunomodulation hematopoietic niche
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00954/full