Application of Monte Carlo simulation to optimise the dosage regimen of meropenem in patients with augmented renal clearance for Pseudomonas aeruginosa infection

Objective: To optimise the dosing regimen of meropenem for treating Pseudomonas aeruginosa (PA) infections in critically ill patients with augmented renal clearance (ARC) using pharmacokinetic/pharmacodynamic (PK/PD) principles and Monte Carlo simulation (MCS). Methods: This research involves an MCS...

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書誌詳細

出版年:	Heliyon
主要な著者:	Jia Hou, Min Zhang, Shu-Qing Ma, Ri-Nan Cong, Jin-Feng Li
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2024-06-01
主題:	Monte Carlo simulation Meropenem Pseudomonas aeruginosa Augmented renal clearance Pharmacokinetic/pharmacodynamic
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2405844024086316