Directional genomic hybridization (dGH™) identifies small inverted duplications in situ

Although fluorescence in situ hybridization (FISH) is a standard approach for characterizing the chromosomal structure involving a region of interest, FISH targeting single chromatids is not routinely performed. However, this latter approach seems principally well-suited to distinguish small, tandem...

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Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Thomas Liehr, Erin Cross, Stefanie Kankel
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	small supernumerary marker chromosomes molecular cytogenetics inverted duplication single-chromatid fluorescence in situ hybridization directional orientation
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2025.1604822/full