Ecofriendly micellar mediated spectrofluorimetric method for ultrasensitive quantification of the antiparkinsonian drug safinamide in pharmaceutical formulation and spiked human plasma

Abstract A novel, highly sensitive and eco-friendly micellar-mediated spectrofluorimetric method was developed and validated for the determination of the novel antiparkinsonian drug safinamide mesylate in the presence of its related precursor impurity, 4-hydroxybenzaldehyde. The proposed approach re...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Engy A. Ibrahim, Hoda M. Marzouk, Maha A. Hegazy, Laila E. Abdel Fattah, Samah S. Saad
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-07-01
Subjects:	Blueness estimation Greenness assessment Micellar-based spectrofluorimetric method Parkinsonism add-on therapy Safinamide mesylate Synthetic precursor impurity
Online Access:	https://doi.org/10.1038/s41598-024-66462-7