Targeting the radiation-induced ARv7-mediated circNHS/miR-512-5p/XRCC5 signaling with Quercetin increases prostate cancer radiosensitivity

Abstract Background Radiation therapy (RT) with androgen deprivation therapy (ADT) is an effective therapy to suppress the locally advanced prostate cancer (PCa). However, we unexpectedly found that RT could also induce the androgen receptor splice variant 7 (ARv7) expression to decrease the radiose...

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發表在:	Journal of Experimental & Clinical Cancer Research
Main Authors:	Dong Chen, Fu-Ju Chou, Yuhchyau Chen, Chi-Ping Huang, Hao Tian, Yaqin Wang, Yuanjie Niu, Bosen You, Shuyuan Yeh, Nianzeng Xing, Chawnshang Chang
格式:	Article
語言:	英语
出版:	BMC 2022-08-01
主題:	ARv7 circNHS miR-512-5p XRCC5 Quercetin Prostate cancer
在線閱讀:	https://doi.org/10.1186/s13046-022-02287-4