The Coronavirus helicase in replication

The coronavirus nonstructural protein (nsp) 13 encodes an RNA helicase (nsp13-HEL) with multiple enzymatic functions, including unwinding and nucleoside phosphatase (NTPase) activities. Attempts for enzymatic inactivation have defined the nsp13-HEL as a critical enzyme for viral replication and a hi...

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Bibliographic Details
Published in:Virus Research
Main Authors: Samantha L. Grimes, Mark R. Denison
Format: Article
Language:English
Published: Elsevier 2024-08-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0168170224000947