Lactate Efflux Inhibition by Syrosingopine/LOD Co‐Loaded Nanozyme for Synergetic Self‐Replenishing Catalytic Cancer Therapy and Immune Microenvironment Remodeling

Abstract An effective systemic mechanism regulates tumor development and progression; thus, a rational design in a one‐stone‐two‐birds strategy is meant for cancer treatment. Herein, a hollow Fe3O4 catalytic nanozyme carrier co‐loading lactate oxidase (LOD) and a clinically‐used hypotensor syrosingo...

Full description

Bibliographic Details

Published in:	Advanced Science
Main Authors:	Shengming Wu, Lehua Xu, Chenlong He, Peng Wang, Jingwen Qin, Fangfang Guo, Yilong Wang
Format:	Article
Language:	English
Published:	Wiley 2023-09-01
Subjects:	lactate efflux nanocatalytic reaction synergetic therapy syrosingopine tumor immunosuppressive microenvironment
Online Access:	https://doi.org/10.1002/advs.202300686