Protocol to study projection-specific circuits in the basal ganglia of adult mice using viral vector tracing, optogenetics, and patch-clamp technique

Summary: Analysis of synaptic strength and plasticity provides functional insights of complicated neural circuits. Here, we describe steps for cell- and projection-specific optogenetic manipulation of divergent basal ganglia circuits using anterograde and retrograde viral vectors. We quantitatively...

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Bibliographic Details

Published in:	STAR Protocols
Main Authors:	Ya-Wei Ji, Xiang-Ying Xu, Cui Yin, Chunyi Zhou, Cheng Xiao
Format:	Article
Language:	English
Published:	Elsevier 2023-09-01
Subjects:	Model Organisms Molecular Biology Neuroscience Molecular/Chemical Probes
Online Access:	http://www.sciencedirect.com/science/article/pii/S266616672300518X