TREM2 deficiency in microglia accelerates photoreceptor cell death and immune cell infiltration following retinal detachment

Abstract Retinal detachment (RD) occurs in several major retinal conditions and often causes irreversible vision loss due to photoreceptor cell death. Retinal residential microglial cells are activated following RD and participate in photoreceptor cell death via direct phagocytosis and the regulatio...

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Bibliographic Details
Published in:Cell Death and Disease
Main Authors: Wenchuan Zhou, Yutong Zhou, Jincan He, Yuqing Rao, Ping Fei, Jing Li
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Online Access:https://doi.org/10.1038/s41419-023-05735-x