Orf132: a critical gene for LSDV replication and its role in Er stress-related apoptosis

Abstract Lumpy skin disease (LSD), caused by the lumpy skin disease virus (LSDV), is an emerging infectious disease in China that primarily affects cattle. LSDV and goatpox virus (GTPV) belong to the Capripoxvirus genus and exhibit high genomic homology, enabling cross-immunogenicity. Comparative ge...

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Bibliographic Details
Published in:Virology Journal
Main Authors: Yongtao Wang, Shiwei Zhang, Hailing Li, Yali Feng, Ying Zhang
Format: Article
Language:English
Published: BMC 2025-05-01
Subjects:
Lumpy skin disease virus
Orf132
Gene deletion
ER stress
Reduced replication
Online Access:https://doi.org/10.1186/s12985-025-02813-8

Internet

https://doi.org/10.1186/s12985-025-02813-8

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