A Preclinical Model to Assess Intestinal Barrier Integrity Using Canine Enteroids and Colonoids

While two-dimensional (2D) cell cultures, such as Caco-2 and Madin–Darby canine kidney (MDCK) cells are widely used in a variety of biological models, these two-dimensional in vitro systems present inherent limitations in replicating the complexities of in vivo biology. Recent progress in three-dime...

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Bibliographic Details

Published in:	Biology
Main Authors:	Megan P. Corbett, Vojtech Gabriel, Vanessa Livania, David Díaz-Regañón, Abigail Ralston, Christopher Zdyrski, Dongjie Liu, Sarah Minkler, Hannah Wickham, Addison Lincoln, Karel Paukner, Todd Atherly, Maria M. Merodio, Dipak Kumar Sahoo, David K. Meyerholz, Karin Allenspach, Jonathan P. Mochel
Format:	Article
Language:	English
Published:	MDPI AG 2025-03-01
Subjects:	transwell canine organoid Caco-2 TEM MDCK
Online Access:	https://www.mdpi.com/2079-7737/14/3/270