Prevalence of treatment resistance and clozapine use in early intervention services

BackgroundTreatment resistance causes significant burden in psychosis. Clozapine is the only evidence-based pharmacologic intervention available for people with treatment-resistant schizophrenia; current guidelines recommend commencement after two unsuccessful trials of standard antipsychotics.AimsT...

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Bibliographic Details

Published in:	BJPsych Open
Main Authors:	Imogen Stokes, Siân Lowri Griffiths, Rowena Jones, Linda Everard, Peter B. Jones, David Fowler, Joanne Hodgekins, Tim Amos, Nick Freemantle, Vimal Sharma, Max Marshall, Swaran P. Singh, Max Birchwood, Rachel Upthegrove
Format:	Article
Language:	English
Published:	Cambridge University Press 2020-09-01
Subjects:	Treatment resistance schizophrenia clozapine early psychosis early intervention
Online Access:	https://www.cambridge.org/core/product/identifier/S2056472420000897/type/journal_article