Ciliary transcription factors and miRNAs precisely regulate Cp110 levels required for ciliary adhesions and ciliogenesis

Upon cell cycle exit, centriole-to-basal body transition facilitates cilia formation. The centriolar protein Cp110 is a regulator of this process and cilia inhibitor, but its positive roles in ciliogenesis remain poorly understood. Using Xenopus we show that Cp110 inhibits cilia formation at high le...

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Bibliographic Details

Published in:	eLife
Main Authors:	Peter Walentek, Ian K Quigley, Dingyuan I Sun, Umeet K Sajjan, Christopher Kintner, Richard M Harland
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2016-09-01
Subjects:	centriole mucociliary epithelia miR-34 miR-449 Foxj1 RFX2
Online Access:	https://elifesciences.org/articles/17557