RAB3B Dictates mTORC1/S6 Signaling in Chordoma and Predicts Response to mTORC1‐Targeted Therapy

Abstract Chordoma, a rare mesenchymal malignancy, exhibits a high tendency to postoperative recurrence and poor prognosis. To date, its tumorigenic regulatory mechanisms remain elusive, leading to a lack of effective therapeutic targets and drug sensitivity indicators. Here, via transcriptome and pr...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Advanced Science
المؤلفون الرئيسيون: Jianxuan Gao, Jiali Jin, Runzhi Huang, Siqiao Wang, Sihui Song, Yu Zhang, Yongai Li, Jun Lin, Zhengyan Chang, Zongqiang Huang, Wei Sun, Huabin Yin, Dianwen Song, Jianru Xiao, Ping Wang, Tong Meng
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Wiley 2025-05-01
الموضوعات:
chordoma
DUSP12
mTORC1 signaling
RAB3B
targeted therapy
الوصول للمادة أونلاين:https://doi.org/10.1002/advs.202415384

الانترنت

https://doi.org/10.1002/advs.202415384

مواد مشابهة