Substrain-specific behavioral variation in female C57BL/6 and C57BL/10 mice

IntroductionInbred mouse strains are essential to biomedical research, yet accumulating mutations and substrain divergence introduce phenotypic variability that can confound experimental outcomes. This study investigates behavioral differences among 13 inbred mouse substrains: eight C57BL/6 (B6) and...

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Bibliographic Details

Published in:	Frontiers in Behavioral Neuroscience
Main Authors:	Celine L. St. Pierre, Natalia M. Gonzales, Greta Sokoloff, Oksana Polesskaya
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2026-04-01
Subjects:	C57BL/10 C57BL/6 fear conditioning forced swim test locomotor response to cocaine prepulse inhibition
Online Access:	https://www.frontiersin.org/articles/10.3389/fnbeh.2026.1805176/full