Uncoupling the Trade-Off between Somatic Proteostasis and Reproduction in Caenorhabditis elegans Models of Polyglutamine Diseases

Caenorhabditis elegans somatic protein homeostasis (proteostasis) is actively remodeled at the onset of reproduction. This proteostatic collapse is regulated cell-nonautonomously by signals from the reproductive system that transmit the commitment to reproduction to somatic cells. Here, we asked whe...

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書誌詳細

出版年:	Frontiers in Molecular Neuroscience
主要な著者:	Anat Ben-Zvi, Netta Shemesh, Nadav Shai, Lana Meshnik, Rotem Katalan
フォーマット:	論文
言語:	英語
出版事項:	Frontiers Media S.A. 2017-04-01
主題:	aging arachidonic acid (AA) Caenorhabditis elegans lipl-4 neurodegenerative diseases proteostasis
オンライン･アクセス:	http://journal.frontiersin.org/article/10.3389/fnmol.2017.00101/full