Optimised production of an anti-fungal antibody in Solanaceae hairy roots to develop new formulations against Candida albicans

Abstract Background Infections caused by fungi are often refractory to conventional therapies and urgently require the development of novel options, such as immunotherapy. To produce therapeutic antibodies, a plant-based expression platform is an attractive biotechnological strategy compared to mamm...

Full description

Bibliographic Details

Published in:	BMC Biotechnology
Main Authors:	Marcello Catellani, Chiara Lico, Mauro Cerasi, Silvia Massa, Carla Bromuro, Antonella Torosantucci, Eugenio Benvenuto, Cristina Capodicasa
Format:	Article
Language:	English
Published:	BMC 2020-03-01
Subjects:	Fungal infections Hairy roots Molecular farming Proteolytic activity Recombinant antibody Rhizosecretion
Online Access:	http://link.springer.com/article/10.1186/s12896-020-00607-0