Transcriptional and epigenetic regulation of follicular T-helper cells and their role in autoimmunity

T-follicular helper (Tfh) cells are a specialized subset of T cells that provide help to B cells and promote the formation of germinal centers (GCs). Tfh cells transmit important signals to B cells that drive class switch recombination, somatic hyper-mutation, the generation of high-affinity antibod...

Full description

Bibliographic Details

Published in:	Autoimmunity
Main Authors:	Hong Qiu, Haijing Wu, Vera Chan, Chak-Sing Lau, Qianjin Lu
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2017-02-01
Subjects:	t-follicular helper transcription factor dna methylation histone modifications micrornas autoimmunity
Online Access:	http://dx.doi.org/10.1080/08916934.2017.1284821