Multi-functional adaptor SKAP1: regulator of integrin activation, the stop-signal, and the proliferation of T cells

T-cell activation is a complex process involving a network of kinases and downstream molecular scaffolds or adaptors that integrate surface signals with effector functions. One key immune-specific adaptor is Src kinase-associated phosphoprotein 1 (SKAP1), which is also known as src kinase-associated...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Chen Liu, Monika Raab, Yirui Gui, Christopher E. Rudd
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-05-01
Subjects:	T-cells signalling adaptor protein integrin activation SKAP1
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1192838/full