Developmental regulation of canonical and small ORF translation from mRNAs

Abstract Background Ribosomal profiling has revealed the translation of thousands of sequences outside annotated protein-coding genes, including small open reading frames of less than 100 codons, and the translational regulation of many genes. Here we present an improved version of Poly-Ribo-Seq and...

Full description

Bibliographic Details

Published in:	Genome Biology
Main Authors:	Pedro Patraquim, Muhammad Ali Shahzad Mumtaz, José Ignacio Pueyo, Julie Louise Aspden, Juan-Pablo Couso
Format:	Article
Language:	English
Published:	BMC 2020-05-01
Subjects:	Ribosomal profiling Poly-Ribo-Seq Ribosomal binding Non-canonical translation Regulation of translation smORFs
Online Access:	http://link.springer.com/article/10.1186/s13059-020-02011-5