Ruthenium Single‐Atom Nanozyme Driven Sonosensitizer with Oxygen Vacancies Enhances Electron–Hole Separation Efficacy and Remodels Tumor Microenvironment for Sonodynamic‐Amplified Ferroptosis

Abstract Sonodynamic therapy (SDT) has emerged as a promising noninvasive approach for tumor therapy. However, the effectiveness of traditional inorganic semiconductor sonosensitizers is hindered by rapid electron (e−) and hole (h+) recombination under ultrasonic (US) stimulation, as well as the hyp...

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Bibliographic Details

Published in:	Advanced Science
Main Authors:	Yang Zhu, Dengliang Wang, Chengzhong Du, Tiantian Wu, Penghui Wei, Hongjia Zheng, Guanting Li, ShunZhe Zheng, Lichao Su, Lingjun Yan, Yongrui Hu, Huimin Wang, Lisen Lin, Chenyu Ding, Xiaoyuan Chen
Format:	Article
Language:	English
Published:	Wiley 2025-06-01
Subjects:	ferroptosis oxygen vacancy single‐atom nanozyme sonodynamic therapy tumor microenvironment
Online Access:	https://doi.org/10.1002/advs.202416997