Dystrophic phenotype improvement in the diaphragm muscle of mdx mice by diacerhein.

Chronic inflammation and oxidative stress are striking features of Duchenne muscular dystrophy disease. Diacerhein is an anthraquinone, which exhibits anti-inflammatory and antioxidant properties. Based on their actions, the present study evaluated the effects of diacerhein against myonecrosis, oxid...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Rafael Dias Mâncio, Túlio de Almeida Hermes, Aline Barbosa Macedo, Daniela Sayuri Mizobuti, Ian Feller Rupcic, Elaine Minatel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0182449&type=printable