4,7-Disubstituted 7<i>H</i>-Pyrrolo[2,3-d]pyrimidines and Their Analogs as Antiviral Agents against Zika Virus

Discovery of compound <b>1</b> as a Zika virus (ZIKV) inhibitor has prompted us to investigate its 7<i>H</i>-pyrrolo[2,3-d]pyrimidine scaffold, revealing structural features that elicit antiviral activity. Furthermore, we have demonstrated that 9<i>H</i>-purine or...

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Bibliographic Details

Published in:	Molecules
Main Authors:	Ruben Soto-Acosta, Eunkyung Jung, Li Qiu, Daniel J. Wilson, Robert J. Geraghty, Liqiang Chen
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Subjects:	Zika virus dengue virus flavivirus antiviral agents
Online Access:	https://www.mdpi.com/1420-3049/26/13/3779