Resveratrol-Enhanced Human Neural Stem Cell-Derived Exosomes Mitigate MPP+-Induced Neurotoxicity Through Activation of AMPK and Nrf2 Pathways and Inhibition of the NLRP3 Inflammasome in SH-SY5Y Cells

Parkinson’s disease (PD) is a progressive neurodegenerative disorder primarily characterized by the loss of dopaminergic neurons in the substantia nigra. Mitochondrial dysfunction, oxidative stress, and neuroinflammation are recognized as critical pathological mechanisms driving neurodegeneration in...

詳細記述

書誌詳細

出版年:	Life
主要な著者:	Ming-Chang Chiang, Yu-Ping Yang, Christopher J. B. Nicol, Tairui Chiang, Chiahui Yen
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2025-02-01
主題:	resveratrol AMPK exosomes MPP<sup>+</sup> neuroprotection
オンライン･アクセス:	https://www.mdpi.com/2075-1729/15/2/294