Myeloid-derived suppressor cells inhibit natural killer cells in myelodysplastic syndromes through the TIGIT/CD155 pathway

ABSTRACTObjective This experiment will explore the role of TIGIT/PVR signaling pathway in the pathogenesis of MDS immune tolerance through in vitro co-culture of NK cells and MDSC cells.Methods Flow cytometry was used to detect the expression percentage of MDSCs and CD155 on MDSCs in the bone marrow...

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Bibliographic Details

Published in:	Hematology
Main Authors:	Jing Yue, Jiaojiao Li, Junlan Ma, Yan Zhai, Li Shen, Wei Zhang, Lijuan Li, Rong Fu
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2023-12-01
Subjects:	Myelodysplastic syndromes immune tolerance TIGIT/CD155 pathway NK cells myeloid-derived suppressor cells
Online Access:	https://www.tandfonline.com/doi/10.1080/16078454.2023.2166333