Assessing mutation accumulation in DNA repair-deficient Listeria monocytogenes: implications for cgMLST cluster thresholds in outbreak analysis

BackgroundListeria (L.) monocytogenes is primarily transmitted via contaminated food and can cause listeriosis, an infection often associated with sepsis and meningitis in at-risk individuals. Accurate outbreak detection relies on whole genome sequencing (WGS) and core genome multilocus sequence typ...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Astrid Füszl, Ariane Pietzka, Patrick Hyden, Tobias Mösenbacher, Anna Stöger, Marion Blaschitz, Silke Stadlbauer, Petra Hasenberger, Stefanie Schindler, Florian Heger, Sonja Pleininger, Alexander Indra
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Subjects:	Listeria monocytogenes listeriosis mutation rate core genome multilocus sequence typing allele threshold outbreak detection
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2025.1530851/full