Single-cell profiling reveals distinct populations of tumor-associated macrophages and metastatic tumor cells in breast cancer brain metastasis

Abstract Breast cancer brain metastasis (BCBM) is a major cause of breast cancer-related mortality, but the molecular mechanisms underlying its progression remain poorly understood. Here, we profiled the tumor immune microenvironment of BCBM at single-cell resolution and identified candidate regulat...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Cell Death and Disease
المؤلفون الرئيسيون: Haoyuan Shi, Jiaxin Chen, Zisheng Wu, Dong-Xu Liu, Jinmei Zhou, Xuexue Wu, Ailing Yang, Shanhu Li, Yanhong Tai, Zefei Jiang, Zhiyuan Hu, Mingshan Zhang, Xiaojie Xu, Lu Pan, Tao Wang
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Nature Publishing Group 2026-04-01
الوصول للمادة أونلاين:https://doi.org/10.1038/s41419-026-08807-w

الانترنت

https://doi.org/10.1038/s41419-026-08807-w

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