HD-PTP is a catalytically inactive tyrosine phosphatase due to a conserved divergence in its phosphatase domain.

The HD-PTP protein has been described as a tumor suppressor candidate and based on its amino acid sequence, categorized as a classical non-transmembrane protein tyrosine phosphatase (PTP). To date, no HD-PTP phosphorylated substrate has been identified and controversial results concerning its cataly...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Marie-Claude Gingras, Yu Ling Zhang, Dmitri Kharitidi, Alastair J Barr, Stefan Knapp, Michel L Tremblay, Arnim Pause
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2009-01-01
Online Access:	http://europepmc.org/articles/PMC2661844?pdf=render