Asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates with α-fluoro-β-keto esters

In the presence of a commercially available Cinchona alkaloid as catalyst, the asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates, with α-fluoro-β-keto esters as nucleophiles, have been successfully developed. A series of important fluorinated adducts, with chiral quaternary carbon ce...

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Bibliographic Details

Published in:	Beilstein Journal of Organic Chemistry
Main Authors:	Lin Yan, Zhiqiang Han, Bo Zhu, Caiyun Yang, Choon-Hong Tan, Zhiyong Jiang
Format:	Article
Language:	English
Published:	Beilstein-Institut 2013-09-01
Subjects:	allylic alkylation asymmetric catalysis fluorine fluoro-β-keto esters Morita–Baylis–Hillman carbonates natural product
Online Access:	https://doi.org/10.3762/bjoc.9.216