METTL3 methylated KIF15 promotes nasopharyngeal carcinoma progression and radiation resistance by blocking ATG7-mediated autophagy through the activation of STAT3 pathway

Background: Resistance to radiotherapy is a major component in the failure of nasopharyngeal carcinoma (NPC) treatment. Enhancing autophagy in nasopharyngeal carcinoma may increase its radiation sensitivity, making it critical to find autophagy-modulating targets. Methods: The level of KIF15 was det...

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Bibliographic Details

Published in:	Translational Oncology
Main Authors:	Siwei Li, Shuibin Wang, Lu Zhang, Xiaofeng Wu, Longfu Tian, Jiahua Zou, Guoliang Pi
Format:	Article
Language:	English
Published:	Elsevier 2025-01-01
Subjects:	KIF15 NPC Radioresistance Autophagy
Online Access:	http://www.sciencedirect.com/science/article/pii/S1936523324002870