Sustained effects on immune cell subsets and autoreactivity in multiple sclerosis patients treated with oral cladribine

IntroductionCladribine tablet therapy is an efficacious treatment for multiple sclerosis (MS). Recently, we showed that one year after the initiation of cladribine treatment, T and B cell crosstalk was impaired, reducing potentially pathogenic effector functions along with a specific reduction of au...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Rikke Holm Hansen, Marina Rode von Essen, Mie Reith Mahler, Stefan Cobanovic, Finn Sellebjerg
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-02-01
Subjects:	immune reconstitution multiple sclerosis cladribine tablets autoreactive T cell responses autoreactive B cells
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1327672/full