The Mechanism of Hyperglycemia-Induced Renal Cell Injury in Diabetic Nephropathy Disease: An Update

Diabetic Nephropathy (DN) is a serious complication of type I and II diabetes. It develops from the initial microproteinuria to end-stage renal failure. The main initiator for DN is chronic hyperglycemia. Hyperglycemia (HG) can stimulate the resident and non-resident renal cells to produce humoral m...

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Bibliographic Details

Published in:	Life
Main Authors:	Tong Wu, Lei Ding, Vivian Andoh, Jiaxin Zhang, Liang Chen
Format:	Article
Language:	English
Published:	MDPI AG 2023-02-01
Subjects:	diabetic nephropathy hyperglycemia mechanism renal cell injury
Online Access:	https://www.mdpi.com/2075-1729/13/2/539