Clinical association and potential molecular mechanisms of neonatal sepsis and necrotizing enterocolitis

BackgroundNecrotizing enterocolitis (NEC) is a severe intestinal disease affecting premature infants, with mortality rates of 20%–30%. Clinical studies have shown that neonatal sepsis (NS) is an independent risk factor for NEC; however, the shared molecular mechanisms and diagnostic biomarkers betwe...

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Bibliographic Details

Published in:	Frontiers in Molecular Biosciences
Main Authors:	Xue Liu, Wenqiang Sun, Jingtao Bian, Yihui Li, Xinyun Jin, Xueping Zhu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	neonatal sepsis necrotizing enterocolitis neutrophil chemotaxis diagnostic biomarkers transcriptional regulatory network
Online Access:	https://www.frontiersin.org/articles/10.3389/fmolb.2025.1662343/full