Sildenafil improves hemodynamic changes caused by acute pulmonary embolism by inhibiting Rho kinase activity
Objective This study examined the effects of sildenafil on acute pulmonary embolism (APE) using a rat model. Methods Sprague–Dawley rats were randomly divided into the sham, pulmonary thromboembolism (PTE), and sildenafil groups. The sham and PTE groups received normal saline once daily via gavage f...
| Published in: | Journal of International Medical Research |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2024-04-01
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| Online Access: | https://doi.org/10.1177/03000605241240938 |