A Different Exosome Secretion Pattern Characterizes Patient-Derived Colorectal Cancer Multicellular Spheroids and Their Mouse Xenografts

Up-to-date in vitro and in vivo preclinical models expressing the patient-specific cancer lineage responsible for CRC and its metastatic behavior and responsiveness to therapy are needed. Exosomes’ role in tumorigenesis and the metastatic process was demonstrated, and the material content and size o...

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Bibliographic Details

Published in:	Biology
Main Authors:	Michela Relucenti, Federica Francescangeli, Maria Laura De Angelis, Vito D’Andrea, Selenia Miglietta, Orlando Donfrancesco, Xiaobo Li, Rui Chen, Ann Zeuner, Giuseppe Familiari
Format:	Article
Language:	English
Published:	MDPI AG 2022-09-01
Subjects:	colorectal cancer exosomes transmission electron microscopy scanning electron microscopy spheroid xenograft
Online Access:	https://www.mdpi.com/2079-7737/11/10/1427